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  Indian J Med Microbiol
 

Figure 2: Histopathology images. Case 1 (a) rectal mucosa infiltrated by malignant cells in a diffuse manner (H and E, ×400). Case 2 (b) rectal mucosa infiltrated by malignant cells in a diffuse manner. Many of the cells have melanin pigment in their cytoplasm (H and E, ×200). Case 3 (c) anal mucosa infiltrated by malignant cells in a diffuse manner. Many of the cells have melanin pigment in their cytoplasm (H and E, 200). All the tumor cells were positive for S-100, HMB45, and Melan A

Figure 2: Histopathology images. Case 1 (a) rectal mucosa infiltrated by malignant cells in a diffuse manner (H and E, ×400). Case 2 (b) rectal mucosa infiltrated by malignant cells in a diffuse manner. Many of the cells have melanin pigment in their cytoplasm (H and E, ×200). Case 3 (c) anal mucosa infiltrated by malignant cells in a diffuse manner. Many of the cells have melanin pigment in their cytoplasm (H and E, 200). All the tumor cells were positive for S-100, HMB45, and Melan A