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  Indian J Med Microbiol
 

Figure 2: Histopathology and immunohistochemistry images of the patient. Section (a) shows tissue fragments capped with respiratory mucosa (H and E, ×4). The subepithelium section (b) shows a cellular lesion which is infiltrating the bone (H and E, ×4). The lesion (c) is composed of sheets of histiocytes, admixed with many lymphocytes and plasma cells. Some of the histiocytes are foamy (H and E, ×20). Some of the histiocytes (d) show emperipolesis (arrow) (H and E, ×40). Immunohistochemistry images show histiocytic cells positive for CD68 (e) and diffusely positive for S100 (x20) (f)

Figure 2: Histopathology and immunohistochemistry images of the patient. Section (a) shows tissue fragments capped with respiratory mucosa (H and E, ×4). The subepithelium section (b) shows a cellular lesion which is infiltrating the bone (H and E, ×4). The lesion (c) is composed of sheets of histiocytes, admixed with many lymphocytes and plasma cells. Some of the histiocytes are foamy (H and E, ×20). Some of the histiocytes (d) show emperipolesis (arrow) (H and E, ×40). Immunohistochemistry images show histiocytic cells positive for CD68 (e) and diffusely positive for S100 (x20) (f)