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  Indian J Med Microbiol
 

Figure 2: Histopathological analysis with hematoxylin and eosin staining (×10 and × 40 views; a and b) revealed lymphoid tissue with effaced architecture of the lymph node with numerous lymphoid follicles, hyalinized atrophic germinal centers with prominent concentric rim of small lymphocytes (onion skinning in mantle zone) and eccentrically placed blood vessels. On immunohistochemistry (c and d), CD3 and CD20 showed admixture of B- and T-cells with polyclonal plasma cells, kappa more than lambda (e and f) suggestive of Castleman disease

Figure 2: Histopathological analysis with hematoxylin and eosin staining (×10 and × 40 views; a and b) revealed lymphoid tissue with effaced architecture of the lymph node with numerous lymphoid follicles, hyalinized atrophic germinal centers with prominent concentric rim of small lymphocytes (onion skinning in mantle zone) and eccentrically placed blood vessels. On immunohistochemistry (c and d), CD3 and CD20 showed admixture of B- and T-cells with polyclonal plasma cells, kappa more than lambda (e and f) suggestive of Castleman disease