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  Indian J Med Microbiol
 

Figure 5: Comparative reduction in reticuloendothelial system uptake with different blocking agents injected 4–24 h before radiolabeled agent (gold nanoparticle labeled immunoglobulin). The use of different blocking agents such as (a) Indian-ink ((b.) Non-specific gammaglobulin (c.) Dextran (d) polygeline (e) hydroxy ethyl Starch to reduce reticuloendothelial system uptake was studied. From the study, it was confirmed that the blocking agent most effective was the unlabeled nonspecific gammaglobulin, which could reduce reticuloendothelial system localization effectively when administered in prior, before the administration of the actual radiolabelled product (gold labeled antibody)

Figure 5: Comparative reduction in reticuloendothelial system uptake with different blocking agents injected 4–24 h before radiolabeled agent (gold nanoparticle labeled immunoglobulin). The use of different blocking agents such as (a) Indian-ink ((b.) Non-specific gammaglobulin (c.) Dextran (d) polygeline (e) hydroxy ethyl Starch to reduce reticuloendothelial system uptake was studied. From the study, it was confirmed that the blocking agent most effective was the unlabeled nonspecific gammaglobulin, which could reduce reticuloendothelial system localization effectively when administered in prior, before the administration of the actual radiolabelled product (gold labeled antibody)