Indian Journal of Nuclear Medicine

: 2021  |  Volume : 36  |  Issue : 2  |  Page : 212--213

Ortner's syndrome associated with takayasu's aortoarteritis identified on fluorodeoxyglucose positron-emission tomography/computed tomography

Piyush Chandra, Satish Nath 
 Department of Nuclear Medicine, MIOT International, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. Piyush Chandra
Department of Nuclear Medicine, MIOT International, Manapakkam, Chennai - 600 056, Tamil Nadu


Cardiovocal syndrome or Ortner's syndrome is hoarseness voice due to left recurrent laryngeal nerve palsy secondary to nerve compression caused by enlarged cardiovascular structures in the mediastinum. We present here an interesting positron-emission tomography/computed tomography image of a patient suspected to have Takayasu's aortoarteritis and presenting with hoarseness of voice.

How to cite this article:
Chandra P, Nath S. Ortner's syndrome associated with takayasu's aortoarteritis identified on fluorodeoxyglucose positron-emission tomography/computed tomography.Indian J Nucl Med 2021;36:212-213

How to cite this URL:
Chandra P, Nath S. Ortner's syndrome associated with takayasu's aortoarteritis identified on fluorodeoxyglucose positron-emission tomography/computed tomography. Indian J Nucl Med [serial online] 2021 [cited 2021 Oct 28 ];36:212-213
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A 41-year-old female presented with chest pain/hoarseness of voice for 6 months. Laboratory investigations revealed only raised erythrocyte sedimentation rate-83 mm in the 1st h and raised C-reactive protein 144.4 mg/l (normal: <10 mg/L). Videolaryngoscopy showed left vocal cord palsy. Volume-rendered three-dimensional computed tomography (CT) aortogram showed sacuular aneurysms involving the aortic arch and infrarenal abdominal aorta [Figure 1]a-yellow arrows]. Mild focal narrowing of the infrarenal aorta was noted just above the bifurcation. The rest of the aortogram was normal. Based on the clinical (no evidence of any pulseless disease) and imaging findings, the patient was diagnosed to have Takayasu's aortoarteritis (TAA) and was referred for positron-emission tomography/CT (PET/CT) for assessing baseline disease activity. Whole-body fluorodeoxyglucose (FDG) PET/CT [[Figure 1]b, black arrows] showed intense focal FDG uptake (Grade 3, SUVmax – 9.31, target-to-liver ratio – 2.66) in the wall of the partially thrombosed saccular aneurysm involving the aortic arch diameter of aneurysm: 4.6 cm and aneurysmal wall thickness: 6.4 mm [[Figure 1]c and [Figure 1]d-long white arrows] and low-grade FDG uptake (Grade 2, SUVmax – 4.24, target-to-liver ratio – 1.23) in the wall of the small saccular aneurysm in infrarenal abdominal aorta diameter of aneurysm: 1.6 cm and aneurysmal wall thickness: 7 mm [Figure 1e and f, short white arrows], with the total vascular score on PET/CT being 6 – suggestive of active vasculitis. Another abnormal finding in PET/CT was asymmetric reduced FDG uptake noted in the adducted left vocal cord consistent with left vocal cord palsy [Figure 1g and h, red arrows]. The patient was started on oral steroids and successfully underwent an endovascular stent grafting of the thoracic ductal aneurysm for impending rupture.{Figure 1}

Although aneurysm formation in TAA is not rare (seen in up to 2.8%–31.9% of the patients), symptomatic aneurysms as a presenting feature of this disease (as seen in this case) are exceedingly rare.[1],[2] This aneurysm formation is probably the result of marked degeneration of the tunica media of the artery and is claimed to be seen more commonly seen in the aorta with little calcification.[3] Risk of rupture of aneurysm related to TAA is very low and surgical repair is advised only if they are >5 cm in diameter.[4],[5] FDG PET/CT is increasingly gaining importance in diagnostic and prognostic assessment of large cell vasculitis.[6] In addition to CT angiography, PET/CT can assess/quantify the whole-body arterial inflammation burden and thereby can be useful for monitoring response to steroids in aneurysms which are managed conservatively.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient (s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

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Conflicts of interest

There are no conflicts of interest.


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