Indian Journal of Nuclear Medicine

INTERESTING IMAGE
Year
: 2020  |  Volume : 35  |  Issue : 4  |  Page : 362--363

18F-fluorodeoxyglucose positron emission tomography–computed tomography in malignant transformation of paget's disease of bone


Raja Senthil1, Vadavattathu Padmanabhan Gangadharan2, Arun Visakh Ramachandran Nair1, Pushpa Mahadevan3, Thara Pratap4 
1 Department of Nuclear Medicine and PET/CT, VPS Lakeshore Hospital, Kochi, Kerala, India
2 Department of Medical Oncology, VPS Lakeshore Hospital, Kochi, Kerala, India
3 Department of Pathology, VPS Lakeshore Hospital, Kochi, Kerala, India
4 Department of Radiology, VPS Lakeshore Hospital, Kochi, Kerala, India

Correspondence Address:
Dr. Raja Senthil
Department of Nuclear Medicine and PET/CT, VPS Lakeshore Hospital, Kochi - 682 040, Kerala
India

Malignant transformation Paget's disease of bone to sarcoma is relatively rare, occurring in approximately 1% of these patients. Although few clinical and imaging findings may help in prediction of malignant transformation, most of them are nonspecific. We describe a case of carcinoma vocal cord and Paget's disease of bone with sarcomatous transformation, where 18F-fluorodeoxyglucose (FDG) positron emission tomography–computed tomography was helpful in accurate diagnosis by demonstrating differential intense FDG uptake in transformed areas of pagetic bone and also FDG-avid osteoblastic pulmonary metastasis.


How to cite this article:
Senthil R, Gangadharan VP, Ramachandran Nair AV, Mahadevan P, Pratap T. 18F-fluorodeoxyglucose positron emission tomography–computed tomography in malignant transformation of paget's disease of bone.Indian J Nucl Med 2020;35:362-363


How to cite this URL:
Senthil R, Gangadharan VP, Ramachandran Nair AV, Mahadevan P, Pratap T. 18F-fluorodeoxyglucose positron emission tomography–computed tomography in malignant transformation of paget's disease of bone. Indian J Nucl Med [serial online] 2020 [cited 2021 Apr 15 ];35:362-363
Available from: https://www.ijnm.in/article.asp?issn=0972-3919;year=2020;volume=35;issue=4;spage=362;epage=363;aulast=Senthil;type=0