Indian Journal of Nuclear Medicine

LETTER TO EDITOR
Year
: 2012  |  Volume : 27  |  Issue : 2  |  Page : 136--137

Assessment of early response to treatment in extrapulmonary tuberculosis: Role of FDG-PET


Manjusha Yadla, Vishnubhotla Sivakumar, Tekchand Kalawat 
 Department of Nephrology and Nuclear Medicine, SVIMS, Tirupati, India

Correspondence Address:
Manjusha Yadla
SVIMS, Tirupati, Andhra Pradesh
India




How to cite this article:
Yadla M, Sivakumar V, Kalawat T. Assessment of early response to treatment in extrapulmonary tuberculosis: Role of FDG-PET.Indian J Nucl Med 2012;27:136-137


How to cite this URL:
Yadla M, Sivakumar V, Kalawat T. Assessment of early response to treatment in extrapulmonary tuberculosis: Role of FDG-PET. Indian J Nucl Med [serial online] 2012 [cited 2022 Aug 10 ];27:136-137
Available from: https://www.ijnm.in/text.asp?2012/27/2/136/110712


Full Text

Sir,

We report an elderly man on dialysis who was evaluated for a suspected bronchogenic carcinoma with fluorodeoxyglucose positron emission tomography (FDG-PET) computed tomography (CT) scan. His scan revealed multiple mediastinal lymph nodes and skeletal lesions [Figure 1] which were later confirmed to be tuberculosis (TB) on TB PCR, Lowenstein-Jensen medium. Three days after initiation of anti-tubercular therapy (ATT), metabolic activity in lymph nodes decreased significantly [Figure 2] though the skeletal lesion activity persisted. Three months after ATT, there was complete resolution of both lymph nodal and skeletal lesions [Figure 3]. Earliest response to ATT on FDG-PET CT was reported to be at the end of eight-week therapy. [1] FDG-PET/CT is the imaging modality that is useful in detecting extra-pulmonary TB and also in assessment of early response to ATT as early as 3 days.{Figure 1}{Figure 2}{Figure 3}

References

1Harisankar C, Mittal BR, Bhattacharya A, Singh B. FDG-PET/CT in diagnosis and early response evaluation of extra-pulmonary tuberculosis in a patient with aplastic anemia. J Postgrad Med 2010;56:219-21.