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Year : 2021  |  Volume : 36  |  Issue : 2  |  Page : 220-222

Paraneoplastic cerebellar degeneration: A dilemma resolved with positron emission tomography/computed tomography


1 Department of Nuclear Medicine, Mahavir Cancer Sansthan and Research Centre, Patna, Bihar, India
2 Department of Surgical Oncology, Mahavir Cancer Sansthan and Research Centre, Patna, Bihar, India
3 Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India
4 Department of Pathology, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Dr. Navin Kumar
Flat No-A-3/10, Purnendu Nagar, Patna - 800 002, Bihar
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijnm.IJNM_211_20

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The case of a 39-year-old woman presented with symptoms of progressive cerebellar degeneration for few months preceding by the diagnosis and treatment of breast cancer. The causative association was revealed with the strong positivity of antineuronal antibody. Because of the multidisciplinary team approach with surgery and adjuvant endocrine treatment, the patient did improve symptomatically and she is alive without any evidence of disease after 22 months following the initial diagnosis of the neurological disorder. Interestingly, neurological symptoms regressed partially after surgery. Early recognition and appropriate combined modality treatment of this rare presentation of breast cancer are imperative as it may be crucial for the disease outcome.


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