Indian Journal of Nuclear Medicine
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INTERESTING IMAGE
Year : 2021  |  Volume : 36  |  Issue : 2  |  Page : 203-204

Paraneoplastic hyperfibrinolysis: detection of occult prostate cancer with 18F-fluorodeoxyglucose positron emission tomography-computed tomography


Department of Nuclear Medicine and PET-CT, Apollo Gleneagles Hospital, Kolkata, West Bengal, India

Correspondence Address:
Dr. Punit Sharma
Department of Nuclear Medicine and PET/CT, Apollo Gleneagles Hospital, 58, Canal Circular Road, Kolkata - 700 054, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijnm.IJNM_195_20

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Hyperfibrinolysis caused by abnormal over-activation of the fibrinolytic system can be associated with occult cancer. We present an interesting case of a 48-year-old man with paraneoplastic hyperfibrinolysis, where 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography-computed tomography (PET-CT) was able to detect occult prostate-specific antigen-negative metastatic prostate cancer as the underlying etiology. This shows that while 18F-FDG PET-CT has overall poor sensitivity for prostate cancer, it can be useful in certain clinical situations.


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