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ORIGINAL ARTICLE
Year : 2021  |  Volume : 36  |  Issue : 1  |  Page : 21-24

Role of technetium-99m-ethylenedicysteine in the calculation of differential renal function: A comparison study with dimercaptosuccinic acid renal scintigraphy


1 Department of Nuclear Medicine, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
2 Department of Nuclear Medicine, School of Medicine, Hasheminejad Hospital, Iran University of Medical Sciences, Tehran, Iran
3 Department of Nuclear Medicine and Molecular Imaging, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran

Correspondence Address:
Dr. Sepideh Hekmat
Vli Asr Avenue, Hasheminejad Hospital, Tehran
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijnm.IJNM_94_20

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Purpose of the Study: The aim of our study was to compare the technetium-99m (Tc-99m)-ethylenedicysteine (EC) renography calculation of differential renal function (DRF) with this measurement using Tc-99m-dimercaptosuccinic acid (DMSA) scintigraphy. Materials and Methods: Patients referred to our department were included in our study, and both DMSA and EC scans were performed for each patient according to the standard imaging protocols. A checklist was filled for each patient. Statistical analysis was performed using correlation and regression methods. Results: Forty-two patients (mean age: 3.6 ± 3.4 years), including 32 boys and 10 girls, participated in our study. The results of EC scintigraphy were significantly correlated with the values of DMSA scintigraphy (P < 0.001). Performing linear regression, EC renography significantly (P < 0.001) predicted the DRF as it was calculated by DMSA scintigraphy (R2 = 0.92, P < 0.001). This test was significant in both male and female subgroups (P < 0.001). Conclusions: Overall, our study findings were similar to the reported results in the other reviewed studies, showing that Tc-99m-EC can be considered as an alternative for DMSA scintigraphy, providing interchangeable results.


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