| INTERESTING IMAGE |
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| Year : 2020 | Volume
: 35
| Issue : 4 | Page : 362-363 |
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18F-fluorodeoxyglucose positron emission tomography–computed tomography in malignant transformation of paget's disease of bone
Raja Senthil1, Vadavattathu Padmanabhan Gangadharan2, Arun Visakh Ramachandran Nair1, Pushpa Mahadevan3, Thara Pratap4
1 Department of Nuclear Medicine and PET/CT, VPS Lakeshore Hospital, Kochi, Kerala, India
2 Department of Medical Oncology, VPS Lakeshore Hospital, Kochi, Kerala, India
3 Department of Pathology, VPS Lakeshore Hospital, Kochi, Kerala, India
4 Department of Radiology, VPS Lakeshore Hospital, Kochi, Kerala, India
Correspondence Address:
Dr. Raja Senthil
Department of Nuclear Medicine and PET/CT, VPS Lakeshore Hospital, Kochi - 682 040, Kerala
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijnm.IJNM_99_20
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Malignant transformation Paget's disease of bone to sarcoma is relatively rare, occurring in approximately 1% of these patients. Although few clinical and imaging findings may help in prediction of malignant transformation, most of them are nonspecific. We describe a case of carcinoma vocal cord and Paget's disease of bone with sarcomatous transformation, where 18F-fluorodeoxyglucose (FDG) positron emission tomography–computed tomography was helpful in accurate diagnosis by demonstrating differential intense FDG uptake in transformed areas of pagetic bone and also FDG-avid osteoblastic pulmonary metastasis.
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