Indian Journal of Nuclear Medicine
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Year : 2018  |  Volume : 33  |  Issue : 1  |  Page : 76-78

Significance of 18F-sodium fluoride positron emission tomography in characterization of POEMS osteosclerotic lesions better than 18F-fluorodeoxyglucose positron emission tomography


1 Department of Nuclear Medicine and PET- CT, cancer control center (KCCC), Shuwaikh, Kuwait
2 Department of Nuclear Medicine and PET- CT, Kuwait cancer control center (KCCC), Shuwaikh, Kuwait; Government College University, Kotwali Road, Faisalabad, Pakistan
3 Government College University, Kotwali Road, Faisalabad, Pakistan

Correspondence Address:
Dr. Rashid Rasheed
Nuclear Medicine Physician, Kuwait Cancer Control Center, Shuwaikh, 22000

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijnm.IJNM_125_17

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Crow-Fukase syndrome (POEMS syndrome) is a rare systemic paraneoplastic syndrome. Bone lesions are manifested by sclerotic osteoblastic lesions often associated with bone pain. Characterization of osseous lesions is always crucial for clinical correlation and better patient management. We present a case where 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET/CT) was unable to characterize a clinically symptomatic patient, and 18F-fluoride PET/CT showed excellent characterization of osteosclerotic lesions. The results were in correlation with already published data and showed that 18F-fluoride PET/CT has better uptake in osteoblastic lesions in POEMS syndrome when compared to18F-FDG PET/CT and have superior imaging quality in assessing the bone lesions.


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