| CASE REPORT |
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| Year : 2017 | Volume
: 32
| Issue : 1 | Page : 46-49 |
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Mixed phenotypic acute leukemia (mixed myeloid/b-cell) with myeloid sarcoma of the thyroid gland: A rare entity with rarer asssociation - detected on fdg pet/ct
Gaurav Khanna1, Nishikant Avinash Damle2, Shipra Agarwal1, Maitrayee Roy1, Deepali Jain1, Soumyaranjan Mallick1, Shamim Ahmed2, Madhavi Tripathi2, Ajay Gogia3
1 Department of Pathology, All Institute of Medical Sciences, New Delhi, India
2 Department of Nuclear Medicine, All Institute of Medical Sciences, New Delhi, India
3 Department of Medical Oncology, All Institute of Medical Sciences, New Delhi, India
Correspondence Address:
Nishikant Avinash Damle
Department of Nuclear Medicine, A.I.I.M.S
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0972-3919.198478
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Mixed phenotypic acute leukemia (MPAL) is a rare clinical entity. MPAL associated with myeloidsarcoma (MS) is still rarer with only three cases mentioned in English literature. MS has been described in myriads of location, most commonly in skin, gums and lymph nodes. Although theoritically possible, it is very rare to find MS involving the thyroid gland. The diagnosis of MS can be elusive, very often masquerades and mislabeled as lymphoma. A high index of clinical suspicion coupled with PET/CT findings along with morphological clues and thorough peripheral blood, and bone marrow evaluation is mandatory for arriving at the definitive diagnosis. We report the case of a 58-year-old female presenting with thyroid swelling that was subsequently diagnosed to be MS of the thyroid with underlying MPAL (mixed myeloid/B-cell) only after 18F-FDG PET/CT, which revealed an unusual abnormal pattern of multifocal intense FDG uptake in the thyroid gland. |
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