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REVIEW ARTICLE
Year : 2015  |  Volume : 30  |  Issue : 4  |  Page : 295-302

Dimercaptosuccinic acid: A multifunctional cost effective agent for imaging and therapy


Department of Nuclear Medicine and PET, Post Graduate Institute of Medical Education and Research, Chandigarh, India

Correspondence Address:
Jaya Shukla
Department of Nuclear Medicine and PET, Post Graduate Institute of Medical Education and Research, Chandigarh - 160 012
India
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Source of Support: Nil., Conflict of Interest: None declared.


DOI: 10.4103/0972-3919.164015

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Dimercaptosuccinic acid (DMSA) is an analog of dimercaprol used as metal chelating moiety in variety of conditions. In nuclear medicine itself two types of Tc-99m DMSA complexes are used, trivalent and pentavalent forms. In this review, we have discussed the mechanism of uptake of both complexes as well as diagnostic and therapeutic application in a clinical scenario.


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