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| LETTER TO EDITOR |
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| Year : 2012 | Volume
: 27
| Issue : 2 | Page : 136-137 |
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Assessment of early response to treatment in extrapulmonary tuberculosis: Role of FDG-PET
Manjusha Yadla, Vishnubhotla Sivakumar, Tekchand Kalawat
Department of Nephrology and Nuclear Medicine, SVIMS, Tirupati, India
| Date of Web Publication | 18-Apr-2013 |
Correspondence Address:
Manjusha Yadla
SVIMS, Tirupati, Andhra Pradesh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0972-3919.110712
How to cite this article:
Yadla M, Sivakumar V, Kalawat T. Assessment of early response to treatment in extrapulmonary tuberculosis: Role of FDG-PET. Indian J Nucl Med 2012;27:136-7 |
How to cite this URL:
Yadla M, Sivakumar V, Kalawat T. Assessment of early response to treatment in extrapulmonary tuberculosis: Role of FDG-PET. Indian J Nucl Med [serial online] 2012 [cited 2022 Jul 6];27:136-7. Available from: https://www.ijnm.in/text.asp?2012/27/2/136/110712 |
Sir,
We report an elderly man on dialysis who was evaluated for a suspected bronchogenic carcinoma with fluorodeoxyglucose positron emission tomography (FDG-PET) computed tomography (CT) scan. His scan revealed multiple mediastinal lymph nodes and skeletal lesions [Figure 1] which were later confirmed to be tuberculosis (TB) on TB PCR, Lowenstein-Jensen medium. Three days after initiation of anti-tubercular therapy (ATT), metabolic activity in lymph nodes decreased significantly [Figure 2] though the skeletal lesion activity persisted. Three months after ATT, there was complete resolution of both lymph nodal and skeletal lesions [Figure 3]. Earliest response to ATT on FDG-PET CT was reported to be at the end of eight-week therapy. [1] FDG-PET/CT is the imaging modality that is useful in detecting extra-pulmonary TB and also in assessment of early response to ATT as early as 3 days. | Figure 1: Fluorodeoxyglucose-positron emission tomography computed tomography scan showing multiple cervical and mediastinal group of lymhnodes along with skeletal lesions
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 | Figure 2: Fluorodeoxyglucose-positron emission tomography computed tomography scan showing decreased tracer uptake in cervical and mediastinal lymphnodes, 3 days after initiation of anti-tubercular therapy
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 | Figure 3: Fluorodeoxyglucose-positron emission tomography computed tomography scan showing normal uptake of tracer in the lymphnodes
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 References | |  |
| 1. | Harisankar C, Mittal BR, Bhattacharya A, Singh B. FDG-PET/CT in diagnosis and early response evaluation of extra-pulmonary tuberculosis in a patient with aplastic anemia. J Postgrad Med 2010;56:219-21. 
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[Figure 1], [Figure 2], [Figure 3]
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