Figure 1: MIP and Axial CT, FDG PET, and fused PET-CT images in a patient with Hodgkin’s disease at (a) Baseline, (b) Post-2 ABVD cycles, (c) Post-4 ABVD cycles, and (d) end of treatment (4ABVD + 2AVD) cycles response assessment PET/CT scans. (a) Stage 2B bulky HD in the mediastinum. (b) Partial response to chemotherapy with a small remnant mediastinal focus (Deauville 4). (c) Further response to chemotherapy with a remaining small mediastinal focus of increased uptake (Deauville 4). The lungs demonstrate diffusely increased tracer uptake with underlying areas of increased parenchymal attenuation at the mid and lower zones. (d) End-of-treatment response assessment: there has been a response to treatment with a further reduction in the size of the residual anterior mediastinal mass and reduction in the remaining focus of increased activity (however this remained Deauville 4). There has been resolution of the previous diffuse tracer uptake in the lungs, and on the CT component of the study, the lungs now appear clear following cessation of bleomycin and treatment with corticosteroids.