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  Indian J Med Microbiol
 

Figure 3: Maximum intensity projection image of a patient with diffuse large B cell lymphoma showing intensely F-18 fluoro-deoxy-glucose (FDG) avid disease below the diaphragm. F-18 FDG positron emission tomography/computed tomography (PET/CT) in addition identified metabolically active disease in subcentimetric left supraclavicular lymph nodes (which could have been missed by CT criteria of 1 cm for involved lymph nodes) and upstages the disease to stage III from stage II. This image highlights the incremental value of F-18 FDG PET/CT in staging patients with lymphoma over CT alone. PET/CT has been shown to be very useful in staging of lymphoma in comparison with anatomic imaging and frequently upstages the disease.[5] Upstaging of disease can have therapeutic and prognostic implications as according to international prognostic index[6] stage III/IV disease is associated with poor prognosis when compared to stage I and II disease

Figure 3: Maximum intensity projection image of a patient with diffuse large B cell lymphoma showing intensely F-18 fluoro-deoxy-glucose (FDG) avid disease below the diaphragm. F-18 FDG positron emission tomography/computed tomography (PET/CT) in addition identified metabolically active disease in subcentimetric left supraclavicular lymph nodes (which could have been missed by CT criteria of 1 cm for involved lymph nodes) and upstages the disease to stage III from stage II. This image highlights the incremental value of F-18 FDG PET/CT in staging patients with lymphoma over CT alone. PET/CT has been shown to be very useful in staging of lymphoma in comparison with anatomic imaging and frequently upstages the disease.<sup>[5]</sup> Upstaging of disease can have therapeutic and prognostic implications as according to international prognostic index<sup>[6]</sup> stage III/IV disease is associated with poor prognosis when compared to stage I and II disease