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  Indian J Med Microbiol
 

Figure 1: Transaxial F-18 fluoro-deoxy-glucose (FDG) positron emission tomography/computed tomography (PET/CT) images of two patients (a and b) with diffuse large B cell lymphoma (DLBCL) showing intense F-18 FDG uptake with maximum standardized uptake value (SUVmax) of 20.3 and 21.6 respectively. Transaxial F-18 FDG PET/CT images of a patient with Hodgkins lymphoma (c and d) showing intensely F-18 FDG avid lymph nodes in the mediastinum and neck (SUVmax = 14.2). The images discusses about F-18 FDG avidity of lymphomas. In general high grade lymphomas are known to be F-18 FDG avid with higher SUVmax and low grade lymphomas are known to be less F-18 FDG avid with lesser SUVmax values.[1] According to International Harmonization Project recommendations HL, DLBCL, Follicular lymphoma, Mantle cell lymphoma are considered to be routinely F-18 FDG avid.[2] anaplastic large cell lymphoma (ALCL) is also considered as 100% F-18 FDG avid according to recent literature[3] and images (e and f) are consistent with this, showing intense F-18 FDG uptake in lymph nodal mass in the mediastinum and mediastinal lymph nodes in two patients with ALCL. Follicular lymphoma, which is a low grade lymphoma is also known to be routinely F-18 FDG avid[4] and the maximum intensity projection image of a patient with Follicular lymphoma (g) shows intensely F-18 FDG avid lymph nodal mass in the abdomen (SUVmax = 21.2). on the contrary low grade lymphomas like small lymphocytic lymphoma (SLL) show very low F-18 FDG avidity as can be noted in transaxial images of the thorax and abdomen (h and i) of a patient with SLL involving b/l axillary and multiple retroperitoneal lymph nodes (SUVmax = 3.4). Due to variable FDG uptake in low-grade lymphomas, staging PET/CT is required to demonstrate the FDG uptake for response assessment at a later stage

Figure 1: Transaxial F-18 fluoro-deoxy-glucose (FDG) positron emission tomography/computed tomography (PET/CT) images of two patients (a and b) with diffuse large B cell lymphoma (DLBCL) showing intense F-18 FDG uptake with maximum standardized uptake value (SUV<sub>max</sub>) of 20.3 and 21.6 respectively. Transaxial F-18 FDG PET/CT images of a patient with Hodgkins lymphoma (c and d) showing intensely F-18 FDG avid lymph nodes in the mediastinum and neck (SUV<sub>max</sub> = 14.2). The images discusses about F-18 FDG avidity of lymphomas. In general high grade lymphomas are known to be F-18 FDG avid with higher SUVmax and low grade lymphomas are known to be less F-18 FDG avid with lesser SUVmax values.<sup>[1]</sup> According to International Harmonization Project recommendations HL, DLBCL, Follicular lymphoma, Mantle cell lymphoma are considered to be routinely F-18 FDG avid.<sup>[2]</sup> anaplastic large cell lymphoma (ALCL) is also considered as 100% F-18 FDG avid according to recent literature<sup>[3]</sup> and images (e and f) are consistent with this, showing intense F-18 FDG uptake in lymph nodal mass in the mediastinum and mediastinal lymph nodes in two patients with ALCL. Follicular lymphoma, which is a low grade lymphoma is also known to be routinely F-18 FDG avid<sup>[4]</sup> and the maximum intensity projection image of a patient with Follicular lymphoma (g) shows intensely F-18 FDG avid lymph nodal mass in the abdomen (SUV<sub>max</sub> = 21.2). on the contrary low grade lymphomas like small lymphocytic lymphoma (SLL) show very low F-18 FDG avidity as can be noted in transaxial images of the thorax and abdomen (h and i) of a patient with SLL involving b/l axillary and multiple retroperitoneal lymph nodes (SUV<sub>max</sub> = 3.4). Due to variable FDG uptake in low-grade lymphomas, staging PET/CT is required to demonstrate the FDG uptake for response assessment at a later stage