Indian Journal of Nuclear Medicine
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   2017| January-March  | Volume 32 | Issue 1  
    Online since January 17, 2017

 
 
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EDITORIAL
Specificity of 68Ga-PSMA PET/CT for prostate cancer - myths and reality
Arun Sasikumar
January-March 2017, 32(1):11-12
DOI:10.4103/0972-3919.198449  PMID:28242976
68Ga-PSMA ligand PET/CT for imaging prostate cancer is a novel imaging technique, which is rapidly gaining popularity. Sufficient evidence has been accumulated in literature regarding the usefulness of 68Ga-PSMA PET/CT in prostate cancer. Recently literature regarding the localization of 68Ga-PSMA PET/CT imaging in non-prostatic malignancies is also published, thus questioning the specificity of the tracer with regards to prostate cancer. This commentary tries to address the issue of specificity of 68Ga-PSMA PET/CT and its relevance in imaging prostate cancer.
  3,877 367 -
COMMENTARY
Unit cost analysis of pet-ct at an apex public sector health care institute in India
SH Gajuryal, A Daga, V Siddharth, CS Bal, S Satpathy
January-March 2017, 32(1):1-6
DOI:10.4103/0972-3919.198438  PMID:28242974
Context: PET/CT scan service is one of the capital intensive and revenue-generating centres of a tertiary care hospital. The cost associated with the provisioning of PET services is dependent upon the unit costs of the resources consumed. Aims: The study aims to determine the cost of providing PET/CT Scan services in a hospital. Methods and Material: This descriptive and observational study was conducted in the Department of Nuclear Medicine at a tertiary apex teaching hospital in New Delhi, India in the year 2014-15. Traditional costing methodology was used for calculating the unit cost of PET/CT scan service. The cost was calculated under two heads that is capital and operating cost. Annualized cost of capital assets was calculated using methodology prescribed by WHO and operating costs was taken on an actual basis. Results: Average number of PET/CT scan performed in a day is 30. The annual cost of providing PET/CT scan services was calculated to be 65,311,719 Indian Rupees (INR) (US$ 1,020,496), while the unit cost of PET scan was calculated to be 9625.92 INR (US$ 150). 3/4th cost was spent on machinery and equipment (75.3%) followed by healthcare personnel (11.37%), electricity (5%), consumables and supplies (4%) engineering maintenance (3.24%), building, furniture and HVAC capital cost (0.76%), and manifold cost (0.05%). Of the total cost, 76% was capital cost while the remaining was operating cost. Conclusions: Total cost for establishing PET/CT scan facility with cyclotron and chemistry module and PET/CT scan without cyclotron and chemistry module was calculated to be INR 610,873,517 (US$9944899) and 226,745,158 (US$3542893), respectively. (US$ 1=INR 64)
  3,019 216 -
CASE SERIES
Rare sites of metastases in prostate cancer detected on ga-68 psma pet/ct scan—a case series
Sugandha Dureja, Parul Thakral, Vineet Pant, Ishita Sen
January-March 2017, 32(1):13-15
DOI:10.4103/0972-3919.198450  PMID:28242977
Ga-68 labeled prostate-specific membrane antigen (PSMA) whole body PET/CT scan is a novel upcoming modality for the evaluation of prostate cancer. We present three cases of prostate cancer showing rare sites of metastases like brain, penis, and liver detected on Ga-68 PSMA PET/CT scan thus emphasizing its role in lesion detection and staging.
  1,571 188 -
CASE REPORTS
Hypothyroidism in mccune–albright syndrome and role of bone scan in management of fibrous dysplasia: An unusual case scenario with review of literature
Narvesh Kumar, Subhash Chand Kheruka, Rani Kunti R Singh, Mudalsha Ravina, Deepanksha Dutta, Sanjay Gambhir
January-March 2017, 32(1):25-29
DOI:10.4103/0972-3919.198462  PMID:28242980
The McCune–Albright syndrome (MAS) is a triad of café-au-lait skin pigmentation, precocious puberty (PP), and polyostotic fibrous dysplasia of bone (FD). In general, FD seems to be the most common component of MAS but very rarely precocious puberty can be found in association with café-au-lait skin pigmentation in the absence of FD (about 1% of the cases). Therefore, a more clinically relevant definition of MAS is fibrous dysplasia of bone (FD) and at least one of the typical hyperfunctioning endocrinopathy and/or café-au-lait spots, with almost any combination possible. Bone scan can be the modality of choice to look for bone disease burden of fibrous dysplasia in most patients of MAS and may change the management accordingly. Most of the cases of MAS reported worldwide are associated with hyperthyroidism, up to best of our knowledge on the basis of literature search in pubmed and Google; no case was reported with hypothyroidism. Herein, we report a 12-year-old girl diagnosed with MAS and associated hypothyroidism.We have also reviewed the MAS related literature.
  1,136 128 -
Radioactive iodine-131 as a definitive treatment in rare association of down syndrome with hyperthyroidism: A case report and review of literature
Shoukat H Khan, Aditya Mahajan, Tanveer A Rather
January-March 2017, 32(1):19-24
DOI:10.4103/0972-3919.198458  PMID:28242979
Down syndrome characterized by trisomy of chromosome 21 is frequently associated with thyroid dysfunctions due to underlying autoimmune disorders. Hypothyroidism is the commonest thyroid dysfunction and hyperthyroidism, usually Graves' disease, is far less common. On literature review, we came across approximately 112 cases reported so far with the first such case report in 1946. The published data from India on hyperthyroidism in Down syndrome is of three case reports. We report one such patient, an adult male of 28 years who was administered Iodine-131 as a definitive treatment after 9-10 years of initial diagnosis.
  1,094 107 -
ORIGINAL ARTICLE
Radio-adaptive response in myocardial perfusion imaging induced by technetium-99m
Mohammad Mehdi Shirazi, Ali Shabestani-Monfared, Maryam Shahidi, Mehrangiz Amiri, Seyed Mohammad Abedi, Sajad Borzoueisileh, Kourosh Ebrahim Nejad Gorji
January-March 2017, 32(1):7-10
DOI:10.4103/0972-3919.198446  PMID:28242975
Purpose of the Study: Low dose radiation will induce adaptation and following exposure to an adaptive dose, the cells are more resistance to following challenging doses. This phenomenon is known as radio-adaptive response. The aim of this study was to investigate the percentage of apoptotic cells in the peripheral blood samples of the patients which undergo myocardial perfusion imaging (MPI) with technetium-99m (Tc-99m) before thallium scan to assess the induction of radio-adaptive response. Materials and Methods: In this study, 97 samples from 74 patients, referred to nuclear medicine center of Mazandaran Heart Hospital for MPI, which had no history of diagnostic, therapeutic, occupational, and radioactive exposures during past 2 years, were provided. The participants were classified into four groups including control, patients which were scanned solely with technetium, the patients which examined by thallium and the last group were the patients that examined by technetium followed by thallium. Then 2 ml Peripheral blood samples were obtained, and after 24 h incubating, the samples were studied by neutral comet assay. Statistical analysis was carried out using Student's t-test along with one-way analysis of variance. Results: The mean percentage of apoptotic cells in the exposed groups were higher than the control. Furthermore, among exposed groups, the apoptotic cells in thallium group were more than others and this index was significantly lower in the group which was undergone technetium administration before thallium scan. Conclusions: These findings suggest that exposure to Tc-99m could induce a radio-adaptive response against the exposure of thallium-201.
  1,061 114 -
CASE REPORTS
Dual tracer pet imaging (68ga-dotatate and 18f-fdg) features in pulmonary carcinoid: Correlation with tumor proliferation index
Dhiraj Bhatkar, Ketaki Utpat, Sandip Basu, Jyotsna M Joshi
January-March 2017, 32(1):39-41
DOI:10.4103/0972-3919.198476  PMID:28242984
Pulmonary carcinoid tumors are rare group of lung neoplasms representing 1% of all the lung tumors. The typical bronchial carcinoids showed higher and more selective uptake of 68Ga-DOTATATE than of 18F-FDG on PET-CT. The Ki-67(MIB-1), a tumor proliferation index is a prognostic marker in neuroendocrine tumors for estimating tumor progression. Atypical carcinoids have higher Ki-67 index and have an increased propensity to metastasize as compared to typical ones.68Ga-DOTATATE PET imaging along with Ki-67 can be correlated for better management of patients with neuroendocrine tumors. We describe the dual tracer imaging features in a patient of pulmonary carcinoid with avid 68Ga-DOTATATE and minimal 18FDG (18Flurodeoxyglucose) uptake diagnosed on the basis of imaging and bronchoscopic biopsy and its correlation with tumor proliferation index.
  954 140 -
INTERESTING IMAGES
18F-FDG pet/ct/mri fusion images showing cranial and peripheral nerve involvement in neurolymphomatosis
Ana Carolina Trevisan, Fernanda Borges Ribeiro, Emerson Nobuyuki Itikawa, Leonardo Santos Alexandre, Felipe Arriva Pitella, Antonio Carlos Santos, Belinda Pinto Simões, Lauro Wichert-Ana
January-March 2017, 32(1):77-78
DOI:10.4103/0972-3919.198502  PMID:28242998
We report a 56-year-old female patient with non-Hodgkin's diffuse large B cell lymphoma (NHL) who, on magnetic resonance imaging (MRI) with a T1 weighted and gadolinium-enhanced imaging, was found to have thickening and infiltration in 75% of peripheral nerves of the patient and enlargements of cranial nerves, possibly related to lymphomatous infiltration. Subsequent positron emission tomography/computed tomography (PET/CT) using 18F-labeled 2-deoxy-2-fluoro-d-glucose (18F-FDG) showed widespread active involvement of the cervical plexus, bilateral peripheral nerves, right femoral nerve, the parasellar region of the skull, and marked hypermetabolism in the left trigeminal ganglia. This case re-emphasizes that while CT and MRI provide anatomical details, 18F-FDG PET/CT images better delineate the metabolic activity of neurolymphomatosis (NL) in the peripheral and central nervous system.
  930 115 -
“Drop” metastases from an operated case of intracranial anaplastic ependymoma identified on fluoro-2-deoxyglucose positron emission tomography/computed tomography
Piyush Chandra, Nilendu Purandare, Sneha Shah, Archi Agrawal, Venkatesh Rangarajan
January-March 2017, 32(1):68-70
DOI:10.4103/0972-3919.198492  PMID:28242994
The seeding of tumor through cerebrospinal fluid (CSF) from primary intracranial tumors is very rare, often goes undetected, and is usually identified only on autopsy. CSF cytology along with magnetic resonance imaging constitutes the standard approach of diagnosing this grave condition. Use of fluoro-2-deoxyglucose positron emission tomography/computed tomography (PET/CT) in indentifying spinal metastases from primary intracranial malignancies is very limited and has been reported in patients with metastatic glioblastoma multiforme and medulloblastomas. We present a rare case of metastatic anaplastic ependymoma to show the potentially clinically utility of PET/CT in diagnosing leptomeningeal or the so-called “drop” metastases.
  939 85 -
CASE REPORTS
Hepatitis c virus-related arthritis: Bone scintigraphic appearances
Gul Ege Aktas, Ali Sarikaya, Ozan Kandemir
January-March 2017, 32(1):30-32
DOI:10.4103/0972-3919.198468  PMID:28242981
A symptomatic joint involvement and arthralgia are frequent in patients with chronic hepatitis C virus (HCV) infection. However, HCV infection-related arthritis (HCVrA) affects up to 4-11% of the subjects suffering from disease. We reported a patient with HCVrA presented with the commonly accepted diagnostic clinical signs and laboratory parameters. The painful joints distinctly demonstrated increased uptake of Tc-99 m methylene diphosphonate in scintigraphy and normal findings in radiography.
  911 70 -
CASE SERIES
Intracranial leptomeningeal carcinomatosis in three cases from breast cancer demonstrated on f-18 fluorodeoxyglucose positron emission tomography/computerized tomography
Hulya Ortapamuk, Mustafa Kemal Demir
January-March 2017, 32(1):16-18
DOI:10.4103/0972-3919.198454  PMID:28242978
Leptomeningeal carcinomatosis (LC) is an uncommon late manifestation of non-central nervous system (CNS) solid tumors. With prolonged survival in solid tumors, an increased frequency of metastases is noted in these tumors too. The detection of tumor cells in the cerebrospinal fluid remains the gold standard. Noninvasively, magnetic resonance imaging is frequently used for the diagnosis of LC. Although its low sensitivity of F-18 fluorodeoxyglucose positron emission tomography/computerized tomography (F-18 FDG PET/CT) on demonstrating CNS lesions, it could be useful in identifying the possibility of LC of breast carcinoma by giving high attention to the meninges. We discuss here three cases all of them having intracranial LC; where 18F-FDG PET/CT study helped us in the diagnosis of LC. To our knowledge, this is the second report about intracranial LC from breast cancer demonstrating on 18F-FDG PET/CT.
  833 95 -
INTERESTING IMAGES
[18F]Fluorodeoxyglucose positron emission tomography reveals a complete remission of refractory metastatic melanoma after therapy with ipilimumab
Anna Yordanova, Carl Schlenkhoff, Holger Palmedo, Markus Essler, Hojjat Ahmadzadehfar
January-March 2017, 32(1):66-67
DOI:10.4103/0972-3919.198490  PMID:28242993
Ipilimumab (YERVOY) is a monoclonal CTLA-4-antibody with anti-tumor-immunogenic effect and is used to treat malignant melanoma. In this case study, we present [18F]Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) images of a 37-year-old woman with metastatic melanoma, who was previously treated with interferon-alpha therapy and dacarbazine and still progressed. After four cycles of ipilimumab, there was a complete remission of the disease with no evidence of vital, FDG-positive tumor tissue. The follow-up for a total of 1 year confirmed the therapeutic success. This report demonstrates that FDG-PET/CT is a reliable imaging method for response monitoring in metastatic melanoma treated with ipilimumab.
  793 94 -
LETTERS TO THE EDITOR
Successful staging of synchronous gastric cancer and diffuse large b-cell lymphoma (dlbcl) using f-18-fluorodeoxyglucose positron emission tomography/computed tomography (fdg pet/ct) based on distinctive levels of metabolic activity between the two malignancies
Hossein Mehdikhani, Sherif Heiba
January-March 2017, 32(1):85-86
DOI:10.4103/0972-3919.198517  PMID:28243002
  755 87 -
CASE REPORTS
Mixed phenotypic acute leukemia (mixed myeloid/b-cell) with myeloid sarcoma of the thyroid gland: A rare entity with rarer asssociation - detected on fdg pet/ct
Gaurav Khanna, Nishikant Avinash Damle, Shipra Agarwal, Maitrayee Roy, Deepali Jain, Soumyaranjan Mallick, Shamim Ahmed, Madhavi Tripathi, Ajay Gogia
January-March 2017, 32(1):46-49
DOI:10.4103/0972-3919.198478  PMID:28242986
Mixed phenotypic acute leukemia (MPAL) is a rare clinical entity. MPAL associated with myeloidsarcoma (MS) is still rarer with only three cases mentioned in English literature. MS has been described in myriads of location, most commonly in skin, gums and lymph nodes. Although theoritically possible, it is very rare to find MS involving the thyroid gland. The diagnosis of MS can be elusive, very often masquerades and mislabeled as lymphoma. A high index of clinical suspicion coupled with PET/CT findings along with morphological clues and thorough peripheral blood, and bone marrow evaluation is mandatory for arriving at the definitive diagnosis. We report the case of a 58-year-old female presenting with thyroid swelling that was subsequently diagnosed to be MS of the thyroid with underlying MPAL (mixed myeloid/B-cell) only after 18F-FDG PET/CT, which revealed an unusual abnormal pattern of multifocal intense FDG uptake in the thyroid gland.
  745 93 -
Renal metastasis and dual (18F-Fluorodeoxyglucose and 131I) avid skeletal metastasis in a patient with papillary thyroid cancer
Prashanth Kulkarni, Pobbi Setty Radhakrishna Gupta Rekha, Meghana Prabhu, Sunil Hejjaji Venkataramarao, Nalini Raju, Naveen Hedne Chandrasekhar, Subramanian Kannan
January-March 2017, 32(1):50-53
DOI:10.4103/0972-3919.198482  PMID:28242987
Differentiated thyroid carcinoma (DTC) though usually behaves in an indolent manner, can have unusual metastatic presentation. Initial presentation of metastatic disease has been reported in 1–12% of DTC being less frequent in papillary (~2%) than in follicular (~10%) thyroid carcinoma. Renal metastasis from DTC is very rare. To our knowledge, only about 30 cases have been reported in the English literature to date. To make clinicians aware that management of such high-risk thyroid cancer frequently requires novel multimodality imaging and therapeutic techniques. A 72-year-old female is described who presented with abdominal pain and bilateral lower limbs swelling. Initial contrast enhanced computed tomography (CT) scan of abdomen showed a well-encapsulated mass in the upper pole of right kidney favoring a renal cell carcinoma. Postright sided radical nephrectomy, histopathology, and immunohistochemistry reports suggested metastatic deposits from thyroid malignancy. 18F-fluorodeoxyglucose (FDG) positron emission tomography-CT demonstrated hypermetabolic nodule in the left lobe of thyroid and a lytic lesion involving left acetabulum suggestive of skeletal metastasis. Subsequently, ultrasound-guided fine needle aspiration cytology of the thyroid nodules in bilateral lobes confirmed thyroid malignancy (Bethesda 6/6). Total thyroidectomy revealed papillary thyroid cancer (PTC) (follicular variant-PTC [FV-PTC]). After surgery, 131I-whole body scan showed iodine avid lytic lesion in the left acetabulum. The present case is a rare scenario of a renal metastasis as the presenting feature of an FV-PTC. Dual avidity in metastatic thyroid cancers (iodine and FDG) is rare and based on the degree of dedifferentiation of the DTC.
  723 104 -
Incidentally detected agenesis of dorsal pancreas on pet/ct: Case report and review of literature
Rasika Kabnurkar, ML Rokade, Kalashree Bandekar, Nikhil Kamat
January-March 2017, 32(1):33-35
DOI:10.4103/0972-3919.198471  PMID:28242982
Agenesis of Dorsal Pancreas (ADP) is a rare congenital anomaly characterized by the absence of body and tail of pancreas. We report a case of incidentally detected ADP on Contrast Enhanced Computed Tomography (CECT) component of Fluorodeoxyglucose Positron Emission Tomography (FDG PET/CT) in a treated case of carcinoma (Ca) tongue with suspected local recurrence. Dependent Intestine Sign, hallmark of ADP on CECT imaging was noted in our patient.
  716 77 -
INTERESTING IMAGES
Detection of thymoma on 99mtc mibi scintigraphy: Revisiting the past
Girish Kumar Parida, Shambo Guha Roy, Anshul Sharma, Chetan D Patel
January-March 2017, 32(1):57-58
DOI:10.4103/0972-3919.198484  PMID:28242989
Although thymoma is a rare tumor, it is the most common anterior mediastinal tumor, usually affecting the adults in their fifth and sixth decade. We present a case of 68-year-old man with history of myocardial infarction, who presented to the cardiology OPD with recent onset of exertional dyspnea. On 99mTc MIBI myocardial perfusion SPECT, there was an extra cardiac accumulation of radiotracer in the anterior mediastinum just above the heart, which later was diagnosed as thymoma on histopathology.
  717 72 -
Candida esophagitis incidentally detected by 18f-fdg pet/ct in metastatic lung adenocarcinoma
N Martinez-Amador, I Martínez-Rodríguez, R Quirce, J Jiménez-Bonilla, I Banzo
January-March 2017, 32(1):71-72
DOI:10.4103/0972-3919.198494  PMID:28242995
The diagnostic significance of esophageal 18F-FDG uptake in oncologic patient is challenging. It may represent normal physiological uptake, inflammation, infection, or neoplasia. We present a patient with a recent diagnosis of non-small cell lung cancer stage IV and esophageal mild uptake on 18F-FDG PET/CT scan. Biopsy of esophageal mucosa demonstrated Candida esophagitis.
  693 78 -
CASE REPORTS
Asymptomatic emphysematous pyelonephritis - positron emission tomography computerized tomography aided diagnostic and therapeutic elucidation
Deepti Pathapati, Pawan Gulabrao Shinkar, Satya Awadhesh kumar, Jha , Palanki Satya Dattatreya, Namrata Chigurupati, MohanaVamsy Chigurupati, Vatturi Venkata Satya Prabhakar Rao
January-March 2017, 32(1):42-45
DOI:10.4103/0972-3919.198477  PMID:28242985
The authors report an interesting coincidental unearthing by 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT ) of a potentially serious medical condition of emphysematous pyelonephritis in a case of nasopharyngeal carcinoma. The management by conservative ureteric stenting and antibiotics was done with gratifying clinical outcome.
  699 71 -
INTERESTING IMAGES
Ocular granulocytic sarcoma as an initial clinical presentation of acute myeloid leukemia identified on flurodeoxyglucose positron emission tomography/computed tomography
Piyush Chandra, Nilendu Purandare, Sneha Shah, Archi Agrawal, Venkatesh Rangarajan
January-March 2017, 32(1):59-60
DOI:10.4103/0972-3919.198485  PMID:28242990
Granulocytic sarcoma (GS) or chloroma, rare extramedullary manifestation of acute myeloid leukemia and not infrequently, can be presenting clinical feature. Multiple studies have demonstrated the clinical utility of fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in early detection and follow-up assessment of GS after chemotherapy. Commonly involved areas include bones, lymph nodes, breasts, and skin and not uncommonly, the disease can be multifocal. We present a rare case of ocular GS, where FDG-PET/CT in addition to the identifying the ocular mass, revealed multiple clinically occult extramedullary lesions.
  688 81 -
Somatostatin receptor spect/ct using 99mTc labeled hynic-toc aids in diagnosis of primary optic nerve sheath meningioma
Piyush Chandra, Nilendu Purandare, Sneha Shah, Archi Agrawal, Venkatesh Rangarajan
January-March 2017, 32(1):63-65
DOI:10.4103/0972-3919.198487  PMID:28242992
Primary optic nerve sheath meningiomas (ONSM) are rare, benign and slow growing tumor involving the intra-orbital/intra-canalicular segment of the optic nerve. Untreated, they can potentially lead to visual deterioration. Magnetic resonance (MR) is the gold standard imaging modality for diagnosing the entity. Often, a clinical dilemma exists to narrow the differential diagnosis of an enhancing intra-orbital mass on MR. Molecular imaging provides a high degree of precision in diagnosing meningioma in view of relatively high levels of somatostatin receptor expression by these tumors. The following case demonstrates the potential clinical utility of somatostatin receptor SPECT using 99mTc- labeled HYNIC-TOC in clinical diagnosis of ONSM.
  678 72 -
CASE REPORTS
Dumbbell gallbladder cholecystitis on tc-99m diisopropyliminodiacetic acid hepatobiliary imaging
Asif Ali Fakhri, Paul David Rodrigue, Aun Hussain, Abbas Taiyebi
January-March 2017, 32(1):36-38
DOI:10.4103/0972-3919.198474  PMID:28242983
We present a case of a 79-year-old immunocompromised female admitted for abdominal pain and sepsis, who had an abdominal computed tomography (CT) showing distal gallbladder fundus wall thickening, pericholecystic edema, and a right posteroinferior hepatic abscess. Subsequent hepatobiliary scintigraphy with Tc-99m diisopropyliminodiacetic acid showed gallbladder filling of the proximal gallbladder fundus, yet no radiotracer filling of the distal gallbladder fundus. Further correlation with the initial CT showed a partial gallbladder stricture and a resultant altered morphology resembling a dumbbell-shaped gallbladder. Percutaneous cholangiogram also confirmed this dumbbell morphology. Nonfilling of radiotracer into the distal end of the dumbbell gallbladder correlating with CT findings of focal gallbladder inflammation indicated that there was a focal inflammation suggesting a distal dumbbell gallbladder cholecystitis. This case demonstrates a unique finding of focal inflammatory pathology involving an anatomic variant - the dumbbell-shaped gallbladder, and the challenges this anatomic variant presents in hepatobiliary scintigraphy image interpretation.
  674 61 -
INTERESTING IMAGES
Pleuroperitoneal mesothelioma: A rare entity on 18f-fdg pet/ct
Manas Kumar Sahoo, Anirban Mukherjee, Girish , Kumar Parida, Krishan Kant Agarwal, Chandrasekhar Bal, Madhavi Tripathi, Chandan Jyoti Das, Shamim Ahmed Shamim
January-March 2017, 32(1):75-76
DOI:10.4103/0972-3919.198499  PMID:28242997
Pleuroperitoneal mesothelioma is an extremely rare entity. Only few cases are reported worldwide. We hereby represent a case of pleural mesothelioma referred for F-18-Fluorodeoxyglucose positron emission tomography/computed tomography for response evaluation. Diffuse F-18-Fluorodeoxyglucose avid peritoneal and omental thickening noted which subsequently turned out to be mesothelial involvement on peritoneal biopsy. This case demonstrates the role of F-18-Fluorodeoxyglucose positron emission tomography/computed tomography in detecting other sites of involvement in case of malignant mesothelioma.
  641 78 -
18F-Fluorodeoxyglucose positron emission tomography/computed tomography scan in an unusual case of lymphoma with secondary involvement of uterine cervix presenting as a pathological fracture
Arun Sasikumar, Ajith Joy, M. R. Pillai, Boben Thomas
January-March 2017, 32(1):54-56
DOI:10.4103/0972-3919.198483  PMID:28242988
A 48-year-old female presented with a pathological fracture of the right femur. 99mTc methylene diphosphonate bone scan revealed multiple areas of increased osteoblastic activity consistent with metastatic disease. Serum electrophoresis revealed monoclonal gammopathy. 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scan revealed metabolically active lesions in bulky uterine cervix and osteolytic skeletal lesions. Unusual pattern of FDG uptake in uterine cervix and osteolytic skeletal lesions warranted a biopsy of the uterine cervix which revealed diffuse large B-cell lymphoma. 18F-FDG PET/CT scan helped in guiding the site of biopsy to reach a final diagnosis in this unusual case of lymphoma with a secondary involvement of uterine cervix presenting as a pathological fracture.
  634 69 -
Thoraco-Abdominal duplication cyst- role tc-99m pertechnetate spect-ct scintigraphy in localising ectopic gastric mucosa
Mudalsha Ravina, Deepanksha Datta, Kasturi Rangan, Ajay Singh Suraj, Sanjay Gambhir
January-March 2017, 32(1):61-62
DOI:10.4103/0972-3919.198486  PMID:28242991
Thoraco-abdominal duplication cyst, a congenital malformation of the posterior primitive foregut rarely presents with anaemia. Ectopic gastric mucosa is seen in around 20%-30% of the enteric duplication cysts. We report the scintigraphic findings of one such case which helped in final diagnosis and management of the patient.
  632 67 -
Tc-99m sulfur colloid lymphoscintigraphy with single-photon emission computed tomography/computed tomography in a case of acquired vulval lymphangiomas
Shruti Tulsyan, Madhavi Tripathi, Kalpa Das, Divya Yadav, Shamim Ahmed Shamim, Nishikant Damle, Chandrasekhar Bal
January-March 2017, 32(1):73-74
DOI:10.4103/0972-3919.198495  PMID:28242996
We describe the lymphoscintigraphy findings of a 25-year-old female patient who was undergoing presurgical workup for lymphangiomas of the vulva. She had a history of treatment for disseminated tuberculosis 6 years back and presented with herpetiform oozing vesicles in the external genitalia. Single-photon emission computed tomography/computed tomography (SPECT/CT) confirmed cutaneous tracer accumulation in the vulval lesions and demonstrated the presence of densely calcified inguinal nodes secondary to healed tuberculosis as the etiology of secondary lymphangioma.
  578 76 -
LETTERS TO THE EDITOR
Intense 18F-Fluoro-deoxyglucose uptake in benign adrenal nodule
Taruna Goel, Maria Mathew D'souza, Arunava Haldar, Sulomo Ejanbemo Ezung, Rajnish Sharma
January-March 2017, 32(1):83-84
DOI:10.4103/0972-3919.198515  PMID:28243001
  537 65 -
Metastatic adenocarcinoma and raised serum ca-125 levels: Looking beyond the ovaries with 18f-fluorodeoxyglucose positron emission tomography/computed tomography
Punit Sharma
January-March 2017, 32(1):79-80
DOI:10.4103/0972-3919.198503  PMID:28242999
  477 57 -
Subependymal spread of glioblastoma multiforme in positron emission tomography/computed tomography
Agostino Chiaravalloti, Orazio Schillaci, Pasqualina Sannino
January-March 2017, 32(1):81-82
DOI:10.4103/0972-3919.198504  PMID:28243000
  473 49 -
OBITUARY
Obituary: Dr. Rajeev Prakash
Arun Malhotra
January-March 2017, 32(1):87-87
DOI:10.4103/0972-3919.198519  
  231 36 -
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