Indian Journal of Nuclear Medicine

CASE REPORT
Year
: 2019  |  Volume : 34  |  Issue : 3  |  Page : 226--229

Sarcoidosis with multiorgan involvement and cutaneous manifestations after colonic adenocarcinoma resection


Ayca Dundar1, Bilge Dundar2, Mevlude Inanc3, Ozlem Canoz5, Fatma Sema Oymak4, Ummuhan Abdulrezzak6 
1 Department of Nuclear Medicine, Erciyes University, Kayseri, Turkeya; Department of Radiology, Mayo Clinic, Rochester, MN, USA
2 Department of Pathology, Erciyes University, Kayseri, Turkey; Department of Pathology, Northwestern University, Chicago, IL, USA
3 Department of Internal Medicine, Division of Oncology, Erciyes University, Kayseri, Turkey
4 Department of Pulmonary Medicine, Erciyes University, Kayseri, Turkey

Correspondence Address:
Dr. Ayca Dundar
150 3rd Street SW, Rochester, MN 55902

Sarcoidosis is a systemic chronic granulomatous disease. It mostly involves the lungs and hilar lymph nodes and produces epithelioid granulomas. Granulomatous (sarcoid) reaction is known to be associated with malignancies; however, it is uncommonly seen with colon carcinomas. Furthermore, systemic sarcoidosis following cancer diagnosis is less commonly seen. To the best of our knowledge, cutaneous sarcoidosis related with an underlying colon carcinoma has not been reported previously in the literature. In this report, we present a very rare case with sarcoidosis development after resection of sigmoid adenocarcinoma, presenting with multiorgan involvement including the skin, eye, joints, and lymph nodes. 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) images showed the skin, lung, spleen, mediastinal, and hilar lymph node involvement. Histopathological examination of skin lesions demonstrated granulomatous dermatitis. This case demonstrates that sarcoidosis can cause intensely FDG-avid lesions on 18F-FDG-PET/CT scans, mimicking metastasis in colon cancer patients. Histopathological evaluation is essential for confirming the diagnosis. 18F-FDG-PET/CT scan provides important information for evaluation of disease extension, progression, and clinical follow-up.


How to cite this article:
Dundar A, Dundar B, Inanc M, Canoz O, Oymak FS, Abdulrezzak U. Sarcoidosis with multiorgan involvement and cutaneous manifestations after colonic adenocarcinoma resection.Indian J Nucl Med 2019;34:226-229


How to cite this URL:
Dundar A, Dundar B, Inanc M, Canoz O, Oymak FS, Abdulrezzak U. Sarcoidosis with multiorgan involvement and cutaneous manifestations after colonic adenocarcinoma resection. Indian J Nucl Med [serial online] 2019 [cited 2019 Aug 23 ];34:226-229
Available from: http://www.ijnm.in/article.asp?issn=0972-3919;year=2019;volume=34;issue=3;spage=226;epage=229;aulast=Dundar;type=0