Indian Journal of Nuclear Medicine

: 2010  |  Volume : 25  |  Issue : 2  |  Page : 67--69

TC 99m MDP bone scan in evaluation of painful scoliosis

Sujit Nilegaonkar1, Sameer Sonar2, Ashish Ranade1, Madhav Khadilkar1,  
1 Shreemati Kashibai Navale Medical College & Hospital, Narhe, Maharashtra, India
2 Ruby Hall Clinic, Pune, Maharashtra, India

Correspondence Address:
Sujit Nilegaonkar
Shreemati Kashibai Navale Medical College and Hospital, Narhe, Pune


A 18-year-old male presented with low back ache. The patient was investigated and was diagnosed to have painful scoliosis. X-ray and other examinations could not reveal any diagnosis. The patient was referred to undergo bone scan on clinical suspicion of osteoid osteoma and to rule out stress fracture if any. Planar bone scan was performed, which showed a lesion in L3 vertebra and was further evaluated with SPECT (Single photon emission computed tomography) study to characterize the lesion. On SPECT examination, the classical features of osteoid osteoma, the double density sign (11), was noted in the pars interarticularis region. These findings were confirmed by a CT scan, which showed a sclerotic lesion in pars interarticularis of L3 vertebra. The patient was posted for operation and was relieved of symptoms in the postoperative follow-up.

How to cite this article:
Nilegaonkar S, Sonar S, Ranade A, Khadilkar M. TC 99m MDP bone scan in evaluation of painful scoliosis.Indian J Nucl Med 2010;25:67-69

How to cite this URL:
Nilegaonkar S, Sonar S, Ranade A, Khadilkar M. TC 99m MDP bone scan in evaluation of painful scoliosis. Indian J Nucl Med [serial online] 2010 [cited 2020 Jul 12 ];25:67-69
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Full Text


Osteoid osteoma is one of the most common benign tumors of the spine and it is also the most common cause of painful scoliosis in adolescents. [1],[2],[3] Up to 20% of osteoid osteomas are found in the spine, of which 60% are located in the lumbar spine and 27% in the cervical spine, 12% in the thoracic spine, and 2% in the sacrum. Osteoid osteoma of the spine must be considered when back ache is associated with muscle spasm and scoliosis. Radiographs often miss the diagnosis due to their small size and the complex anatomy of the spine.

Two thirds of spinal osteoid osteomas represent as painful scoliosis. It is, however, very common to miss the diagnosis and the patient may be subjected to treatments, such as bracing, adding discomfort to the patient. [4]

 Case Report

An 18-year-old male presented with low back ache since 1 year. The patient had scoliosis. Typical evening raising plain X-ray was done and was inconclusive. Bone scan was ordered to evaluate boney pain.

A three-phase bone scan was performed. The planar images revealed a focal solitary lesion in the L3 vertebra. The lesion was further evaluated with SPECT study for further characterization, which revealed a lesion in the L3 vertebral pars interarticularis region. Central focal hot spot with peripheral decremental uptake was noted in L3 vertebral pars interarticularis.

A CT scan was performed to precisely localize the lesion and to confirm the diagnosis. CT scan showed osteosclerotic lesion in the L3 vertebral pars interarticularis region [Figure 1],[Figure 2],[Figure 3],[Figure 4].{Figure 1}{Figure 2}{Figure 3}{Figure 4}


Osteoid osteoma is a benign osteoblastic neoplasm most often seen in young males, frequently in the first 3 decades of life and may be found in the cortical or cancellous bone with a further 5% reported as subperiosteal, and multicentric foci were also reported. [5],[6]

Preliminary diagnosis carries some difficulties, mostly due to unawareness of the condition, leading to delay in the management. The first imaging procedure is usually the plain radiography, [4],[6],[7],[8] which shows different pictures depending on the location of the lesion (whether medullary or cortical) and the degree of reactive sclerosis surrounding the nidus. The lesions in the pelvis and spine are usually difficult to identify by plain radiographs. [4],[6],[7],[9] The most important plain radiographic differential diagnosis includes osteoblastoma, Brodies abscess, stress fracture, and enostosis. [1],[4]

Although radioisotope imaging is not pathognomonic for osteoid osteoma, it can be very useful in diagnosis and anatomic location, and intraoperative and postoperative identification. [3],[4],[5],[7],[8],[9],[10] The sign of "double density image" is usually created, [11] which is fairly typical of osteoid osteoma. [5],[7]

A CT scan is essential for optimal planning before surgery is performed and for postoperative confirmation of complete resection.

Treatment can be surgical or conservative. To achieve a surgical cure the entire nidus must be removed completely; medical management of osteoid osteoma is well recognized and is usually needed whenever the lesion is inaccessible even with the most carefully planned surgical exposures, or is adjacent to vital neurovascular structures, or when the patient refuses any operative interference.

In conclusion, any child or adolescent with scoliosis complaining of back pain, particularly long-standing, should be investigated thoroughly, keeping in mind the possibility of osteoid osteoma and a bone scan should be ordered as a primary investigation because a plain radiograph may not be significant in detecting these lesions.


1Leone A, Costantini A, Guglielmi G, Settecasi C, Priolo F. Primary bone tumors and pseudotumors of the lumbosacral spine. Rays 2000;25:89-103.
2Heiman ML, Cooley CJ, Bradford DS. Osteoid osteoma of a vertebral body: Report of a case with extension across the intervertebral disk. Clin Orthop 1976;118:159-63.
3Schmitz A, Diedrich O, Schmitt O. Sacral osteoid osteoma: A rare cause of back pain in childhood and adolescence. Klin Padiatr 2000;212:110-2.
4Janin Y, Epstein JA, Carras R, Khan A. Osteoid osteomas and osteoblastomas of the spine. Neurosurgery 1981;8:31-8.
5Carnesale PG. Benign tumors of bone. In: Canale ST, editor. Campbell's Operative Orthopaedics. St. Louis: Mosby; 1998. p. 691-2.
6Huvos AG. Bone tumors, diagnosis, treatment and prognosis. Philadelphia: W. B. Saunders Company; 1979. p. 18-29.
7Gitelis S, Schajowicz F. Osteoid osteoma and osteoblastoma. Orthop Clin North Am 1989;20:313-25.
8Campanacci M, Ruggieri P, Gasbarrini A, Ferraro A, Campanacci L. Osteoid Osteoma: Direct visual identification and intralesional excision of the nidus with minimal removal of bone. J Bone Joint Surg Br 1999;81:814-20.
9Banzo I, Montero A, Uriarte I, Vallina NK, Hernandez A, Guede C, et al. Localization by bone SPET of osteoid osteoma in the vertebral lamina. Rev Esp Med Nucl 1999;18:47-9.
10Assenmacher S, Voggenreiter G, Klaes W, Nast-Kolb D. Osteoid osteoma: A diagnostic and therapeutic problem. Chirurg 2000;71:319-25.
11Helms CA. Osteoid osteoma. The double density sign. Clin Orthop Relat Res 1987;222:167-73.