Indian Journal of Nuclear Medicine
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CASE REPORT
Year : 2020  |  Volume : 35  |  Issue : 1  |  Page : 58-60

Prostate-specific membrane antigen-expressing hepatic lesion: Metastatic or hepatocellular carcinoma


1 Department of Nuclear Medicine and PET.CT, Tata Medical Center, Kolkata, West Bengal, India
2 Department of Oncopathology, Tata Medical Center, Kolkata, West Bengal, India
3 Department of Radiation Oncology, Tata Medical Center, Kolkata, West Bengal, India

Correspondence Address:
Dr. Jayanta Das
Department of Nuclear Medicine and PET-CT, Tata Medical Center, 14 Mar, Kolkata - 700 160, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijnm.IJNM_145_19

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Prostate-specific membrane antigen (PSMA) is a glycosylated type-II transmembrane protein highly expressed in certain tumor cells. It has emerged as a novel radiotracer for evaluation of prostate cancer. Increased PSMA expression in isolated liver lesion is a diagnostic challenge. Solitary liver metastasis from prostate cancer is rare. On the other hand, PSMA avid primary hepatocellular carcinoma (HCC) has been reported in literature. We report a case of PSMA expressing atypical HCC with normal alphafeto protein (AFP) and raised prostate specific antigen (PSA).


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