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CASE REPORT
Year : 2020  |  Volume : 35  |  Issue : 1  |  Page : 54-57

Multimodality imaging of anti-contactin-associated protein-like 2 antibody-induced nonparaneoplastic limbic encephalitis: Complementary role of fluorine-18 fluorodeoxyglucose positron emission tomography and magnetic resonance imaging


1 Department of Nuclear Medicine, SGPGIMS, Lucknow, Uttar Pradesh, India
2 Department of Radiodiagnosis, SGPGIMS, Lucknow, Uttar Pradesh, India

Correspondence Address:
Dr. Manish Ora
F Block, Department of Nuclear Medicine, SGPGIMS, Lucknow - 226 014, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijnm.IJNM_178_19

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Autoimmune limbic encephalitis (AE) is an autoimmune-mediated inflammation typically affecting the medial temporal lobes and other limbic structures (cingulate gyrus, orbital cortex, and hypothalamus). It can be associated with underlying malignancy as a paraneoplastic syndrome. Nonparaneoplastic AE is a difficult disease to diagnose and often requires the collaboration of multiple modalities for effective diagnosis and treatment. We describe an interesting case of contactin-associated protein-like 2 antibody-associated nonparaneoplastic limbic encephalitis on fluorine-18 fluorodeoxyglucose positron emission tomography and magnetic resonance imaging.


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