Indian Journal of Nuclear Medicine
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Year : 2019  |  Volume : 34  |  Issue : 1  |  Page : 66-68

Positron emission tomography-computed tomography in a case of POEMS syndrome

Department of Nuclear Medicine, Hospital Infanta Cristina, Badajoz, Spain

Correspondence Address:
Dr. Jose Rafael Infante
Department of Nuclear Medicine, Hospital Infanta Cristina, Carretera De Portugal S/N, E-06080, Badajoz
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijnm.IJNM_120_18

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The POEMS syndrome is a rare and multisystemic disease characterized by the presence of polyneuropathy, organomegaly, endocrinopathy, presence of M protein, and alterations in the skin. The existence of bone lesions is frequent, being generally blastic or mixed and rarely lytic. We present the case of a 54-year-old male patient diagnosed with POEMS syndrome, with atypical presence of lytic lesions, who was referred for an 18F-fluorodeoxyglucose positron emission tomography-computed tomography (PET-CT) study for initial staging of the process. There were several hypermetabolic foci coinciding with bone lesions, reaching a maximum standardized uptake value of 15 at the level of the right iliac bone with associated soft-tissue mass. PET-CT is an adequate tool for evaluation, diagnosis, and monitoring of the pathology. The scan allows the detection and selection for its biopsy of bone lesions and lymphadenopathies.

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