Indian Journal of Nuclear Medicine
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Year : 2018  |  Volume : 33  |  Issue : 3  |  Page : 250-252

18F-Fluorodeoxyglucose positron emission tomography-computed tomography imaging of inferior vena cava tumor thrombus extending into the right atrium in a patient with cholangiocarcinoma treated with 90Y-Microspheres

1 Nuclear Medicine Unit, “Santa Maria Goretti” Hospital, Latina, Italy
2 Division of Interventional Radiology, S. Camillo Hospital, Rome, Italy
3 Department of Biomedicine and Prevention, University Tor Vergata, Rome; IRCCS Neuromed, Pozzilli, Italy

Correspondence Address:
Luca Filippi
Nuclear Medicine Unit, “Santa Maria Goretti” Hospital, Via Canova, Latina
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijnm.IJNM_50_18

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We present a case of a 42-year-old male patient affected by unresectable, chemorefractory cholangiocarcinoma, with prior placement of biliary stent. Because of the absence of extrahepatic metastases, he was submitted to liver-direct therapy with 90Y-microspheres. 18F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) performed before the procedure showed intense tracer uptake in the hepatic lesion and along the biliary stent. The patient underwent radioembolization with 90Y-resin spheres (1.1 GBq). 18F-FDG PET-CT, acquired 6 weeks after the procedure, showed no response of the hepatic lesion and the appearance of an area of markedly increased uptake extending through the inferior vena cava into the right atrium, confirmed as extensive tumor thrombus at the enhanced multislice CT subsequently performed. 18F-FDG PET-CT proved to be a useful imaging tool not only for the evaluation of metabolic response but also for the early detection of extrahepatic progression after 90Y-radioembolization.

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