Indian Journal of Nuclear Medicine
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REVIEW ARTICLE
Year : 2017  |  Volume : 32  |  Issue : 4  |  Page : 259-265

Clinical pearls: Etiologies of superscan appearance on Fluorine-18-Fludeoxyglucose positron emission tomography-computed tomography


Division of Nuclear Medicine, Department of Radiology, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL, USA

Correspondence Address:
John Joseph Manov
Department of Nuclear Medicine, University of Miami Miller School of Medicine, Jackson Memorial Hospital, 1611 NW 12th Avenue, West Wing #279, Miami, FL 33136
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijnm.IJNM_56_17

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The term “superscan” usually refers to a characteristic pattern on skeletal scintigraphy consisting of symmetrically intense and diffuse radiotracer uptake in the skeleton with absent or diminished visualization of the genitourinary system and soft tissues. Superscans and superscan-like appearances have also been described on fluorine-18-fludeoxyglucose positron emission tomography-computed tomography (18-F-FDG PET/CT). We review reported cases of 18-F-FDG PET/CT superscans and propose criteria for differentiating pathologic superscans from physiologic causes. Knowledge of the 18-F-FDG PET/CT superscan, its reported pathologic causes, its benign imitators, and its clinical implications is important to the nuclear medicine physician or radiologist specializing in the interpretation of nuclear studies to avoid several diagnostic pitfalls.


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