Indian Journal of Nuclear Medicine
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Year : 2017  |  Volume : 32  |  Issue : 2  |  Page : 145-147

Increased F-FDG uptake in bilateral gynecomastia secondary to feminizing adrenal tumor: A rare case report and review of literature


1 Radiation Medicine Centre, Bhabha Atomic Research Centre, TMC Annexe, Jerbai Wadia Road, Parel, Mumbai, India
2 Global Hospital, Parel, Mumbai, India

Correspondence Address:
Priyanka Verma
Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Centre Annexe, Jerbai Wadia Road, Parel, Mumbai
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-3919.202246

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A 21 year old male who presented with painful enlargement of both the breasts and a hyperestrogenic state, was found to harbor a heterogeneous mass arising from the right adrenal on contrast enhanced Computed Tomography abdomen. The mass was hypermetabolic with no regional, nodal or distant metastases on Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography /Computed Tomography examination. Notably, substantial tracer uptake was seen in bilateral gynecomastia. The patient underwent a right adrenalectomy with the histopathology report confirming adrenocortical carcinoma. This case demonstrates utility of FDG PET/CT in adrenocortical carcinoma. However, when interpreting FDG PET/CT as a staging tool in oncological male patients, one should consider gynecomastia as a possible cause for increased FDG uptake in the breast as it may lead to a false positive interpretation.


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