Indian Journal of Nuclear Medicine
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Year : 2017  |  Volume : 32  |  Issue : 1  |  Page : 77-78

18F-FDG pet/ct/mri fusion images showing cranial and peripheral nerve involvement in neurolymphomatosis


1 Nuclear Medicine and Molecular Imaging Section, Ribeirão Preto Medical School, University of São Paulo, São Paulo; Bioengineering Interunits Postgraduation Program, São Carlos School of Engineering, University of São Paulo, São Carlos, Brazil
2 Division of Hematology of the Internal Medicine Department and Postgraduation Program. Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil
3 Nuclear Medicine and Molecular Imaging Section, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil

Correspondence Address:
Ana Carolina Trevisan
Seção de Medicina Nuclear do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto – SP, Brasil. Av. Bandeirantes, 3900 - Monte Alegre, Ribeirão Preto - SP
Brazil
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-3919.198502

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We report a 56-year-old female patient with non-Hodgkin's diffuse large B cell lymphoma (NHL) who, on magnetic resonance imaging (MRI) with a T1 weighted and gadolinium-enhanced imaging, was found to have thickening and infiltration in 75% of peripheral nerves of the patient and enlargements of cranial nerves, possibly related to lymphomatous infiltration. Subsequent positron emission tomography/computed tomography (PET/CT) using 18F-labeled 2-deoxy-2-fluoro-d-glucose (18F-FDG) showed widespread active involvement of the cervical plexus, bilateral peripheral nerves, right femoral nerve, the parasellar region of the skull, and marked hypermetabolism in the left trigeminal ganglia. This case re-emphasizes that while CT and MRI provide anatomical details, 18F-FDG PET/CT images better delineate the metabolic activity of neurolymphomatosis (NL) in the peripheral and central nervous system.


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