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Year : 2017  |  Volume : 32  |  Issue : 1  |  Page : 54-56

18F-Fluorodeoxyglucose positron emission tomography/computed tomography scan in an unusual case of lymphoma with secondary involvement of uterine cervix presenting as a pathological fracture


1 Department of Nuclear Medicine and PET/CT, KIMS-DDNMRC, KIMS Hospital, Thiruvananthapuram, Kerala, India
2 Department of Medical Oncology, KIMS Hospital, Thiruvananthapuram, Kerala, India

Correspondence Address:
Arun Sasikumar
KIMS-DDNMRC, KIMS Hospital North Block, Anayara P. O, Thiruvananthapuram - 695 029, Kerala
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-3919.198483

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A 48-year-old female presented with a pathological fracture of the right femur. 99mTc methylene diphosphonate bone scan revealed multiple areas of increased osteoblastic activity consistent with metastatic disease. Serum electrophoresis revealed monoclonal gammopathy. 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scan revealed metabolically active lesions in bulky uterine cervix and osteolytic skeletal lesions. Unusual pattern of FDG uptake in uterine cervix and osteolytic skeletal lesions warranted a biopsy of the uterine cervix which revealed diffuse large B-cell lymphoma. 18F-FDG PET/CT scan helped in guiding the site of biopsy to reach a final diagnosis in this unusual case of lymphoma with a secondary involvement of uterine cervix presenting as a pathological fracture.


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