Indian Journal of Nuclear Medicine
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CASE REPORT
Year : 2016  |  Volume : 31  |  Issue : 1  |  Page : 55-58

Change in the diagnosis from classical Hodgkin's lymphoma to anaplastic large cell lymphoma by 18 F flourodeoxyglucose positron emission tomography/computed tomography: Importance of recognising disease pattern on imaging and immunohistochemistry


1 Department of Nuclear Medicine, Global Hospitals, Chennai, Tamil Nadu, India
2 Department of Pathology, Global Hospitals, Chennai, Tamil Nadu, India
3 Department of Medical Oncology, SIMS Vadapalani, Chennai, Tamil Nadu, India

Correspondence Address:
Sumati Sundaraiya
Department of Nuclear Medicine, Global Hospitals, Chennai - 600 100, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-3919.172364

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Anaplastic large cell lymphoma (ALCL) is a rare type of nonHodgkin's lymphoma (NHL), but one of the most common subtypes of T-cell lymphoma. It is an aggressive T-cell lymphoma, and some ALCL may mimic less aggressive classical HL histopathlogically. It may be misdiagnosed unless careful immunohistochemical examination is performed. As the prognosis and management of these two lymphomas vary significantly, it is important to make a correct diagnosis. We describe a case who was diagnosed as classical HL by histopathological examination of cervical lymph node, in whom 18 F-flouro deoxyglucose positron emission tomography/computed tomography appearances were unusual for HL and warranted review of histopathology that revealed anaplastic lymphoma kinase-1 negative anaplastic large T-cell lymphoma, Hodgkin-like variant, thereby changing the management.


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