Indian Journal of Nuclear Medicine
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CASE REPORT
Year : 2015  |  Volume : 30  |  Issue : 3  |  Page : 268-271

Incidental detection of prostate-specific antigen-negative metastatic prostate cancer initially presented with solitary pulmonary nodule on fluorodeoxyglucose positron emission tomography/computed tomography


1 Department of Nuclear Medicine, Bezmialem Vakif University, Istanbul, Turkey
2 Department of Pathology, Bezmialem Vakif University, Istanbul, Turkey
3 Department of Thoracic Surgery, Bezmialem Vakif University, Istanbul, Turkey
4 Department of Urology, Bezmialem Vakif University Department of Urology, Bezmialem Vakif University, Istanbul, Turkey
5 Division of Medical Oncology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey

Correspondence Address:
Ezgi Basak Erdogan
Department of Nuclear Medicine, Faculty of Medicine, Bezmialem Vakif University, Adnan Menderes Bulvari, Vatan Caddesi, 34093 Fatih, Istanbul
Turkey
Mehmet Aydin
Department of Nuclear Medicine, Bezmialem Vakif University, Istanbul
Turkey
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-3919.151655

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A 71-year-old male patient with solitary pulmonary nodule underwent fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) showing slightly increased FDG uptake in this nodule. In addition, PET/CT detected hypermetabolic sclerotic bone lesions in the right second rib and 7 th thoracic vertebrae, which were interpreted as possible metastases, and mildly increased FDG uptake in the prostate gland highly suspicious of malignancy. The patient's prostate-specific antigen (PSA) level was within normal range (3.8 ng/dL). The histopathological examination of the lung nodule and right second rib lesion proved metastases from prostate cancer, then the prostate biopsy-confirmed prostate adenocarcinoma. The unique feature of this case is to emphasize the importance of performing PET/CT for solitary pulmonary nodule in detecting PSA-negative metastatic prostate cancer. This case indicated that it should be kept in mind that, even if the PSA is negative, a lung metastasis of prostate cancer may be an underlying cause in patients evaluated for solitary pulmonary nodule by FDG PET/CT.


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