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ORIGINAL ARTICLE
Year : 2015  |  Volume : 30  |  Issue : 3  |  Page : 199-203

The role of fluorine-18 fluorodeoxyglucose positron emission tomography in patients with mycosis fungoides


1 Department of Nuclear Medicine, Kuwait Cancer Control Center, Kuwait City, Kuwait
2 Department of Pathology, Kuwait Cancer Control Center, Kuwait City, Kuwait
3 Department of Medical Oncology, Kuwait Cancer Control Center, Kuwait City, Kuwait
4 Department of Medicine, Kuwait University, Kuwait City, Kuwait

Correspondence Address:
Sharjeel Usmani
Department of Nuclear Medicine, Kuwait Cancer Control Center, Kuwait City
Kuwait
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-3919.158527

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Purpose: The aim of the present study is to evaluate the possible role of fluorine-18 fluorodeoxyglucose positron emission tomography-computed tomography ( 18 F-FDG PET-CT) in the management of mycosis fungoides (MF). Materials and Methods: Nineteen patients (mean age, 40.6 years; median age 41 years; 16 males and 3 females) with risk of secondary lymph node (LN) involvement (those with large cell transformation, tumors, erythroderma, or enlarged LNs on physical examination) were included in the study. All patients underwent PET-CT scan by injecting 0.06 mCi/kg of F18 FDG. The maximum standard uptake value (SUVmax) was recorded for each patient. Results: The 18 F-FDG PET-CT was positive in 15 patients. PET-CT detected local cutaneous disease in 13 cases. The range of SUVmax is 2.8-14.1. Out of 19 patients, hypermetabolic adenopathy is found in 9 patients and visceral involvement in one. Conclusions: Although the study population is small our findings suggests that 18 F-FDG PET-CT can detect cutaneous and extracutaneous lesions in MF and may guide biopsies especially in patients with risk of secondary LN involvement.


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