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REVIEW ARTICLE
Year : 2014  |  Volume : 29  |  Issue : 4  |  Page : 210-221

Brain perfusion single photon emission computed tomography in major psychiatric disorders: From basics to clinical practice


1 Department of Nuclear Medicine, Brain imaging Centre, Dakshi Diagnostics, Lucknow, Uttar Pradesh, India
2 Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India

Correspondence Address:
Amburanjan Santra
D/4E Souraniloy Housing Complex, 1 Kailash Ghosh Road, Kolkata - 700 008, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-3919.142622

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Brain single photon emission computed tomography (SPECT) is a well-established and reliable method to assess brain function through measurement of regional cerebral blood flow (rCBF). It can be used to define a patient's pathophysiological status when neurological or psychiatric symptoms cannot be explained by anatomical neuroimaging findings. Though there is ample evidence validating brain SPECT as a technique to track human behavior and correlating psychiatric disorders with dysfunction of specific brain regions, only few psychiatrists have adopted brain SPECT in routine clinical practice. It can be utilized to evaluate the involvement of brain regions in a particular patient, to individualize treatment on basis of SPECT findings, to monitor the treatment response and modify treatment, if necessary. In this article, we have reviewed the available studies in this regard from existing literature and tried to present the evidence for establishing the clinical role of brain SPECT in major psychiatric illnesses.


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