Indian Journal of Nuclear Medicine
Home | About IJNM | Search | Current Issue | Past Issues | Instructions | Ahead of Print | Online submissionLogin 
Indian Journal of Nuclear Medicine
  Editorial Board | Subscribe | Advertise | Contact
Users Online: 1253 Print this page  Email this page Small font size Default font size Increase font size
ORIGINAL ARTICLE
Year : 2007  |  Volume : 22  |  Issue : 2  |  Page : 60-64

The impact of F-18 fluorodeoxyghicose positron emission tomography in the management of patients with lung nodule and associated risk of morbidity or indeterminate results at biopsy


1 Department of Nuclear Medicine, IRCCS-Ospedale Maggiore, Milan, Italy
2 Department of Nuclear Medicine, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland
3 Unit of Thoracic Surgery, IRCCS-Ospedale Maggiore, Milan, Italy

Correspondence Address:
Massimo Castellani
Department of Nuclear Medicine, Ospedale Maggiore di Milano, Via F. Sforza 35, 20122, Milan
Italy
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

The purpose of the study was to assess the clinical impact of positron emission tomography (PET) with fluorine-18 fluorodeoxyglucose (FDG) in the management of patients who were unsuitable candidates for transthoracic needle aspiration (TTNA) of solitary lung nodules. The PET study results of forty-six patients were retrospectively evaluated. The major indications for PET study were the inaccessibility of the lesion or the small size of the lung nodules for TTNA (n=16), a previous undiagnostic or a denied procedure (n=12), or massive chronic obstructive pulmonary disease (COPD) (n=13). A PET scan was also performed in 3 elderly patients and in 2 subjects treated with anticoagulant drugs. The patient's clinical history and the results of computed tomography (CT) were also evaluated to assess thepre-test likelihood of cancer (high, low or indeterminate probability) and their influence on the decision making process in comparison with PET results. No treatment was performed in 19/23 (83%) patients with negative PET studies and low or indeterminate pre-test likelihood for cancer, whereas a surgical assessment of lung nodules was obtained in the remaining 4 patients, all with high probability for tumour. All 19 patients with focal FDG lung nodule uptake had surgery or chemoradiotherapy irrespective of probability of cancer, whereas an antimicrobial therapy for infectious disease was performed in the 4 patients with equivocal PET studies and low or indeterminate likelihood. The results of FDG-PET study may influence the management of patients unsuitable for TTNA, whenever CT images do not strongly suggest cancer.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed397    
    Printed54    
    Emailed0    
    PDF Downloaded49    
    Comments [Add]    

Recommend this journal